Amnesia, Anterograde remember new info. retrograde difficulty in remembering events that happened before amnesia. organic: damage to brain structure e.g.frontal lobe & excessive alcohol consumption. Functional amnesia psychological factors e.g. fugue state & loss of explicit memory - deliberately and consciously recalled. Reed & Squire 1989. MRI scans on 4 amnesic all hippo, damage. 2 temporal lobe damage who had severe Retrograde amnesia. Low pop V, no conclusion, no comparison of normal pop. Difficult to generalise.
Alzheimer’s, progressive. Impaired memory, thoughts & speech. Plaques and tangles, Amyloid precursor protein broken down into beta amyloid protein 42 = build-up of plaques. Selkoe 2000 plaques start to form before symptoms = problems in the communication between neurones. Build-up of plaque and Alzheimer’s is weak and hard to explain, Murphy & LeVine 2010, presence of β-amyloid protein 42 early in the disease starts a chain of events that leads to the illness, yet to be properly tested. Snyder 2005, β-amyloid protein 42 interferes with NDMA, NT Alzheimer’s could occur as it is a chemical change which causes your learning to be affected Cleary et al (2005) did an experiment where rats were injected with β-amyloid disrupts memory. Genetic predisposition: Levy-Lahad eta al in 1995 early signs of the Alzheimer’s gene on chromosome 1. Schellenberg et al (1992) chromosome 14 Ertekin-Taner et al 2000 C 10 , not isolated, all genes involved in producung more beta amyloid. St George-Hislop 2000 half of all Alzheimer’s patients have no known relative with disorder = genetic influence is small.
Comments
No comments have yet been made