All or nothing response: For a response to be given, the stimulus must be above the threshold potential.
The size of an action potential is always the same, however the frequency differs.
Resting Potential: sodium/potassium ion pumps use ATP to pump 3 Na+ out for every 2K+ ions in, also leak out due to permeability.
CELL CYTOPLASM CONTAINS LARGE ANIONS
Local Currents
Local currents involve the movement of ions along the neurone: Occur in the cytoplasm of the neurone. These local currents cause sodium ion channels further along to open.
1. Action potential occurs, Na+ channels open.
2. Na+ diffuses across membrane into neurone.
3. This causes sodium to diffuse sideways. The change in pd causes Na+ channels to open further along to neurone.
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