Case Studies in Medicine Through Time

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Medieval: Black Death

  • It first hit, in Britain, 1348 
  • It was caused by the Medieval causes
  • It was actually caused by rats and lice
  • It was prevented by 
  • It could be attempted in treating by
  • It could be prevented by 
  • Examples of symptoms were buboes
  • The Black Death started in China and then spread across to Europe

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Renaissance: The Great Plague in 1665

  • Symptoms were the same to the Black Death
  • People would try and prevent the plague by having public days of fasting and prayer ordered by the King
  • People would pray for the sick and would put magical / religious charms on the buboes to let the pus out as well as bleeding and purging
  • People believed that miasma spread disease but it was actually via rats and lice

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Renaissance: Harvey and Blood Circulation

  • He discovered blood circulation via dissecting cold-blooded animals
  • This was a breakthrough because it was the first step into breaking away from the church and starting scientific developments
  • Harvey had read about previous doctors' work, such as Galen, and developed his theory from there
  • A limitation was that because he dissected animals and not humans, because dissecting humans was not allowed, so Harvey was not able to know everything about the human heart
  • An example of what Harvey didn't know about the human heart is that he did not know how blood moved from the arteries to the veins

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Industrial: Jenner and Vaccination

  • Jenner made the first major breakthrough, discovering the smallpox vaccintion
  • He observed that people who contracted cowpox didn't contract smallpox
  • He experimented by injecting a small inactive dose of cowpox and they didn't get smallpox
  • The vaccination became a new breakthrough in medical history
  • The word vaccination was used because "vacca" in latin means cow
  • He then went on to publish his work in 1798

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Industrial: The Cholera Outbreak in 1854

  • When cholera first broke out it killed approximately 14,000 people
  • The Cholera Outbreak was solved in Broad Street by John Snow
  • John Snow was a physician who observed cholera in Broad Street
  • A way people treated cholera was the Public Health Acts which ordered for an improvement in Public Health but it was not for another 20 years that it was enforced!
  • Snow found that cholera was caused by dirty water
  • He then made a water pump to produce clean water
  • The water pump reduced death rate massively  

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Modern Day: Penicillin

  • In 1928, Alexander Fleming discovered that penicillin and went onto publish a book on his discovery
  • In 1938, Howard Florey and Ernst Chain read about Fleming's work and realised it could be very effective
  • Florey and Chain got £25 funding from the government
  • It wasn't until 1941 when they tested penicillin on a man with septicaemia and it worked
  • In 1941, just post Pearl Harbor so Florey went to America and soon American Government was having penicillin mass-produced

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Modern Day: Lung Cancer

  • Lung Cancer is caused by smoking - 90%
  • By the 1900's there was over 40,000 cases of lung cancer per year
  • Some cases of lung cancer were caused by passive smoking
  • Only 10% of people live for more than 5 years once diagnosed
  • Lung Cancer can be treated by chemotherapy, radiotherapy, immunotherapy or surgery 
  • The only prevention would be not smoking however other than that there is no prevention

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