The Hypothalmus & neurotransmitters-Kaplan & Woodside(1987) damaged the hypothalmus of rats who then couldn't stop eating. Seems NE makes you eat (preferably carbs) Serotonin induces feelings of satiation. Carraso(2000) found lowere levels of serotonin in Bulimic patients.
Genes-Kendler(1999) concordance rate of 23% for MZtwins & 9% for DZ. Askevold & Heiberg(1979) 50% concordance rate for MZ same environment. Hollander(1984) 55% MZ & 7% DZ. No evidence for twins reared apart diff. to evaluate.
Evaluation-Rates for MZtwins are always higher-suggesting a genetic link. Studies from rats can't be generalised to humans (the rats weren't vomiting). Concordance rates vary enormously, if it was all genes MZ rates should be 100%. Bulimics secretive so self report not reliable. Reductionist & deterministic. Eating behaviour is also influenced by cognitive, social & cultural factors.
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