Schizophrenia is the result of an excess of dopamine at synaptic sites
Evidence for this can be found in
Phenothiazines- block dopamine at receptors and work in aliviating symptoms of schizophrenia- but not for everyone
L-dopa- used to treat parkinsons by increasing dopamine- but it produces schizophrenia symptoms
Wong et al- PET scans found increased dopamine receptor density in non drug treated schizophrenia patients
However Farde et al could not replicate these results in later studies
reductionist to assume it is purely dopamine
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