Therapies for Schizophrenia

a brief outline of the therapies for sz with pros and cons

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  • Created by: HarryJV
  • Created on: 15-05-12 11:29
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Effectiveness - whether it is successful in predicting the desired outcome.
Appropriateness - whether a treatment is suitable for the purpose in which it is being used.
Biological Treatments:
Conventional (Typical) Antipsychotics - block and reduce number of D2 receptor sites, long
term blockage of dopamine. Treats positive symptoms.
Effective - long term effect.
Effective - Low relapse rates, number of symptoms decreased.
Not effective - DAVIDSON ET AL (2004) drugs reduce long term institutionalisation
but argued 'revolving door' pattern (admission, discharge, readmission).
Not effective - BENNETT (2006) drugs delay relapse rather than prevent it. 40%
relapse rates in first year, 15% in other years.
Not appropriate - Negative side effects i.e. symptoms of Parkinson's (stiffness,
Not appropriate - GUALTIERI (1991) found that they destroy a part of the brain,
irreversible. Occurs in 30% and increases with prolonged usage.
Not appropriate - can cause tardive dyskinesia (slow, involuntarily, repetitive body
Atypical Antipsychotics - partially block D2 receptors acting on dopamine and serotonin,
dissociate to allow normal dopamine transmission.. Treats negative symptoms.
Effective - DELIMA ET AL (2005) supports the treatment of negative symptoms.
Not effective - short term effect.
Not effective - RZEWASKA (2002) symptoms return if patients stop taking drugs.
Not effective - LEUCHT ET AL (1999) meta-analysis, not as 'more effective' as
previously thought.
Appropriate - injectable, long lasting.
Not appropriate - weight gain and loss of sexual drive possible side effects.
Appropriate, lower side effects.
Electro Convulsive Therapy - electrical discharge stimulates neurotransmitters in brain. 2-3
times a week, 6-8 weeks, short term treatment. Outdated procedure.
THARYAN & ADAMS (2005) meta-analysis investigating effectiveness of ECT. Reliable,
consistency throughout meta-analysis, results can be used to help SZ patients.
Invalid, studies not conducted by researchers themselves.
Only short term effectiveness.
Not appropriate - ethical issues i.e. harm to the patient.

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Psychological Treatments:
CBT (Cognitive Behavioural Therapy) - abnormal behaviour i.e. SZ caused by irrational
thoughts about their future, themselves and their world, aim of therapy is to challenge.
Coping Enhancement Strategy, form of CBT, therapist focuses on one hallucination/
delusion, client and therapist identify additional coping strategies for it. Reality testing,
individual asked to identify irrational beliefs in alternative ways. Activity designed to test
whether beliefs are real performed by patients, intention to realise beliefs are irrational.…read more


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