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Schizophrenia 2. Biological Explanations

Genetic Explanations

Family Studies.

Gottesman 1991 carried out meta analysis looking at the rates of Schizophrenia in
MZ (identical) and DZ ( twin. Found an MZ twin is more likely to get Schizophrenia if
the other twin is a sufferer. Mz has a high concordance rate…

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provide a MC concordance rate that is many times higher than the DZ concordance

Evaluation: Twin studies

Enviroment for MZ and DZ twins are similar.
Shared Environment ­ although not as high at MZ twins, DZ twins do show an
increased concordance rate of schizophrenia in comparison to the…

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Joseph 2004 claims in countries like Denmark and Us, potential adoptive parents
would have been informed on genetic background of children prior to selection.
Kringlen 1987- as these adoptive parents know their background, it does wonder
who would adopt a child with a schizophrenic biological parent.

Neurochemical Explanations

Dopamine Hypothesis:…

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Because studies into dopamine activity in the brains of schizophrenics are carried out
after they have died its impossible to tell if increased dopamine causes Schizophrenia
or if Schizophrenia causing changes to the brain.

Brain scans ­ PET scans track the levels of dopamine in the brains of living patients.…

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- MRI scans record radio waves from the brain, they are computerised to form a 3D
picture of the brains structure.

- They reveal definite structural abnormalities in the brains of schizophrenics.

- EVALUATION: Massive break through as it provides pictures of the living brain where
previous research had relied…


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