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Gene mutation
Mutation: any change to the quantity of the structure of the DNA of an organism

Mutations in body cells are not passed to next generation
Mutations occurring during formation of gametes may be inherited, which is the basis of
discontinuous variation.

Discontinuous variation: Variation within a population in…

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Cause of mutations
Gene mutations can arise spontaneously during DNA replication, and are permanent. They
occur without outside influence.

Basic mutation rate is increased by outside factors ­ MUTAGENIC AGENTS/ MUTAGENS:

High energy radiation that can disrupt DNA molecule
Chemicals that alter the DNA structure or interfere with transcription



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