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Heart and heart disease




Heart and Heart disease
Summary question
Pg.89 topic 5.1
What is the name of the blood vessel that supplies the heart muscle with
oxygenated blood?
Coronary artery

State whether the blood in each of the following structures is oxygenated or
deoxygenated.
a) Vena cava
Deoxygenated
b)…

Page 2

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Heart and heart disease




In each case, name the structure being described.
a) On contraction it forces blood into the ventricles
Atria
b) It acts as the heart's pacemaker.
Sinoatrial node
c) It relays a wave of excitation to the apex of the heart.
Bundle of his

After a period…

Page 3

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Heart and heart disease




determined by the heart itself [5]
d) An interventricular septal defect is an opening in the wall (septum) that separates
the left and right ventricles. Suggest and explain the effect of this defect on
blood flow through the heart [2]

4c) explain how smoking and a…

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Heart and heart disease




Fatty streaks/deposits adhere to the wall of arteries;
Atheroma/atherosclerosis/plaque;
Narrows lumen of artery;
Damages endothelium;
Can lead to the formation of thrombus/blood clot;

Describe how atheroma can lead to an aneurysm. [2]
Weakens artery walls;
So that it swells/burst;

Explain how you would calculate the magnification.…

Page 5

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Heart and heart disease




Receptor site for adrenaline/moradrenaline/stops adrenaline/noradrenaline binding;

Describe how an atheroma is formed and how it can lead to a myocardial infraction.
[6]
Fatty material/ foam cells/cholesterol in artery wall/ under endothelium;
Creates turbulence/damage to lining of artery;
Formation of plaques/atherosclerosis/narrows lumen of artery;
Turbulence increase risk…

Page 6

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Heart and heart disease




Cigarette smoking and a diet high in saturated fat increase the risk of myocardial
infarction. Explain why. [6]
Carbon monoxide combines with haemoglobin/causes less oxygen to be transported;
Decreases concentration of antioxidants in blood;
Increases the damage done to artery walls;
Blood clot may occur;
Blood…

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