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Similarities
- Both are polypeptides formed from amino acid monomers.
- Both have peptide bonds formed in condensation reactions.
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Differences
- Haemoglobin has a prosthetic haem group that contains iron to bond with oxygen, collagen has no prosthetic groups.
- Haemoglobin is a globular protein with hydrophobic groups turned towards the inside of the molecule and hydrophilic groups turned towards the inside, collagen is a fibrous protein.
- Hb is 4 polypeptide chains, collagen is 3 chains.
- Collagen has a structural role in the body; tendons, bones, cartilage, connective tissue. Haemoglobin has a metabolic role in transporting oxygen and carbon dioxide.
- Hb forms balls of chains in a globular structure, whereas collagen has a helix rope like structure.
- Hb is soluble, collagen insoluble.
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