UTI mind map

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  • Created by: ElaineT29
  • Created on: 19-10-22 22:24
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  • LUTI = Bladder and below
    • Bacteria ascend ureters from lower tract
      • bacterias unique pili allow them to adhere to renal parenchyma
        • bacterial proliferation
          • UUTI (Pyelonephritis) = above bladder
          • Impairment of body's usual defence system, stagnant urine, iatrogenic growth surfaces allow bacterial accumulation
            • PREDISPOSING FACTORS = immunocompromised, diabetes, elderly, female, pregnancy, obstruction, catheters
  • Usual pathogens = E.coli, enterococcus, Klebsiella
  • PATHOGENESIS
  • Clinical Findings
  • Inflammatory response initiated
    • Inflammation of renal parenchyma and capsule
      • Costovertebral angle tenderness
      • Flank Pain
    • Cytokines released systemically
      • Increased WBC on FBC
      • Fever, Malaise, nausea or vomiting
    • WBC's onsite release enzymes
      • Urine findings = increased WBC, +bacterial culture, +nitrates, +leukocytes, Foul smelling urine, cloudy, hematuria
        • Inflammatory response initiated
          • Inflammation of renal parenchyma and capsule
            • Costovertebral angle tenderness
            • Flank Pain
          • Cytokines released systemically
            • Increased WBC on FBC
            • Fever, Malaise, nausea or vomiting
          • WBC's onsite release enzymes
            • Urine findings = increased WBC, +bacterial culture, +nitrates, +leukocytes, Foul smelling urine, cloudy, hematuria
              • Pathogens use enzymes to reduce nitrate to nitrite
        • Pathogens use enzymes to reduce nitrate to nitrite
  • Unique response of altered fluid status, electrolytes and mental status likely as a result of increased inflammatory cytokines
    • Delirium in Elderly
  • Bacterial colony irritates urinary epithelium
    • Dysuria
    • Stimulation of urinary reflex
      • Urgency
      • Frequency

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