POTs (2004)
- Created by: nhurdiss
- Created on: 01-04-19 17:21
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- POTs (2004)
- Aim
- To evaluate the effectiveness of three treatments for OCD relative to a placebo group
- Findings
- Ppts treated with CBT + SSRI or CBT alone showed substantially higher probability of improvement
- MEAN CY-BOCS SCORES AFTER 12 WEEKS
- Combined; 11.2
- Placebo; 21.5
- SSRI; 16.5
- 50% difference between placebo and CBT treatment remission rates
- Procedure
- 12 week controlled clinical trial conducted in 3 academic centres across the USA
- 112 out-patient volunteers aged 7-17, diagnosed with OCD and having a CY-BOCS score of over 16
- All ppts. screened for learning difficulty, tourettes, all had IQ of over 80
- 112 out-patient volunteers aged 7-17, diagnosed with OCD and having a CY-BOCS score of over 16
- Ppts were randomly assigned to one of four conditions, into groups of 28
- SSRI ALONE
- CBT ALONE
- CBT + SSRI
- PLACEBO
- 12 week controlled clinical trial conducted in 3 academic centres across the USA
- Conclusions
- OCD patients have a higher chance of entering remission with CBT based treatment
- SSRI still remains effective as it showed more improvement than placebo
- AO3
- Aim
- RELIABLE; standardised procedures
- ETHICAL; procedures reviewed by ethical board at each stage
- APPLICABLE; OCD is a common paediatric disorder and findings can aid the treatment and prevent comorbidity
- INDIVIDUAL DIFFERENCE- S.D for combined at end was 8.6
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