POTs (2004)

  • Created by: nhurdiss
  • Created on: 01-04-19 17:21
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  • POTs (2004)
    • Aim
      • To evaluate the effectiveness of three treatments for OCD relative to a placebo group
    • Findings
      • Ppts treated with CBT + SSRI or CBT alone showed substantially higher probability of improvement
      • MEAN CY-BOCS SCORES AFTER 12 WEEKS
        • Combined; 11.2
        • Placebo; 21.5
        • SSRI; 16.5
      • 50% difference between placebo and CBT treatment remission rates
    • Procedure
      • 12 week controlled clinical trial conducted in 3 academic centres across the USA
        • 112 out-patient volunteers aged 7-17, diagnosed with OCD and having a CY-BOCS score of over 16
          • All ppts. screened for learning difficulty, tourettes, all had IQ of over 80
      • Ppts were randomly assigned to one of four conditions, into groups of 28
        • SSRI ALONE
        • CBT ALONE
        • CBT + SSRI
        • PLACEBO
    • Conclusions
      • OCD patients have a higher chance of entering remission with CBT based treatment
      • SSRI still remains effective as it showed more improvement than placebo
    • AO3
  • RELIABLE; standardised procedures
  • ETHICAL; procedures reviewed by ethical board at each stage
  • APPLICABLE; OCD is a common paediatric disorder and findings can aid the treatment and prevent comorbidity
  • INDIVIDUAL DIFFERENCE- S.D for combined at end was 8.6

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