Osteoporosis

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  • Created by: MazzaW
  • Created on: 15-11-19 13:51
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  • Osteoporosis
    • Risk factors
      • Female
      • Post-menopausal
      • Elderly
      • Low BMI
      • Tall
      • Steroids
      • Cushing's syndrome
      • FH
      • Smoking
      • Alcohol
      • Hypo-gonadism
      • Secondary osteoporosis
        • Malabsorption
        • Hepatic or renal disease
        • Endocrine disease
          • Cushing's
          • Hypo-gonadism
          • Hyperpara-thyroidism
          • Thyrotoxicosis
        • Drugs
          • Steroids
          • Anti-convulsants
        • Rheumatoid arthritis
        • Osteogenesis imperfecta
    • Diagnosis
      • BMD score
        • T-score < -2.5 = osteoporosis
        • T-score -1 to -2.5 = osteopenia
        • Measured by DEXA scan at hip and spine
        • Z-score is compared to age-matched population
      • Previous pathological fracture
        • Low impact
        • Often at hip/wrist
    • Patho-physiology
      • Reduced bone mass
      • Normal biochemistry of bone
    • Mgmt
      • Calcium and vitamin D supplements
      • Lifestyle interventions
        • Reducing falls/fracture risk
        • Exercise
        • Stop smoking + alcohol
      • Bis-phosphonates
      • HRT
      • PTH injections

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