Monoclonal Anitbodies. (4.3.2)
- Created by: KatRushtonCollier
- Created on: 14-05-18 18:26
View mindmap
- Monoclonal Antibodies. (4.3.2)
- Producing Monoclonal antibodies. (4.3.2.1)
- Antibodies produced are specific to one binding site on one protein antigen and so are able to target a specific chemical or specific cells in the body.
- Specific antibodies are produced by stimulating mouse lymphocytes
- The lymphocytes are combined with a kind of tumour cell to make a cell called a hybridoma cell and that this hybridoma cell can both divide and make the antibody.
- Monoclonal antibodies are formed from a single clone of cells.
- Single hybridoma cells can be cloned to produce many identical cells that all produce the same antibody and that a large amount of the antibody can be collected and purified.
- Malignant tumour cells are cancers. They invade neighbouring tissues and spread to different parts of the body (via the bloodstream) where they form secondary tumours
- Uses of monoclonal antibodies (4.3.2.2)
- Discuss the importance of monoclonal antibodies and evaluate the advantages and disadvantages associated with their use.
- Describe some ways in which monoclonal antibodies can be used, including:
- treating diseases such as cancer
- Measuring the levels of hormones and other chemicals in blood.
- Pregnancy tests.
- To detect pathogens.
- Locating or identifying specific molecules in a cell or tissue by binding to them with a fluorescent dye.
- Producing Monoclonal antibodies. (4.3.2.1)
Comments
No comments have yet been made