Johne's Disease
- Created by: crmarshall98
- Created on: 16-08-22 16:18
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- Johne's Disease
- Definition
- chronic enteritis - M.paratuberculosis
- small intestines and ileum thickening
- carrier ---> subclinical --> clinical
- Sources
- faeces from shedding cattle/ sheep
- colostrum/milk from infected cattle
- environment
- develop 2-6yo
- Clinical signs
- diarrhoea
- decreased production
- weight loss
- oedema
- DDx
- nutritional problem
- liver fluke
- LDA
- parasitic gastroenteritis
- salmonellosis
- peritonitis
- Diagnostics
- detect MAP
- shedding not until later disease
- can use pooled sample
- faecal culture- good detection but £££
- faecal PCR- good if its present
- detect immune response
- only Ab evaluation available
- more sensitive early infection
- detect MAP
- Treatment
- none- needs management
- usually cull ASAP
- prevention/manage
- transmission
- sepearte youngstock up to 1yo from source
- main focus in herds that tes +ve
- biosecurity
- prevent buying in
- know sources for buying
- test individuals
- keep closed herd
- test and cull - blood Ab
- identify high risks - individual milk sample Ab testing - cull high risk
- Vaccination
- prevent disease not infection
- can import vaccine with license
- may interfere with TB test
- Untitled
- transmission
- Definition
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