Immune Response- Edexcel unit 4

  • Created by: Bukky
  • Created on: 26-12-12 16:44
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  • Immune Response
    • Specific
      • T helper cells activate B cells
        • T helper- release substrates to activate B cells T killer and phagocytes
        • B cells are covered in antibodies that bind to antigens  forming an antigen -antibody complex
          • This along with the substrates released from T helper activates B cells that divide into B memory and plasma
      • Phagocytes activate T cells
        • Receptors in T cell bind to APC
          • When T cell receptor meets complementary antigen it binds
            • This activates the T cell and causes it tio differentiate
      • B effector cells/ Plasma cells make antibodies to specific antigens
        • Plasma are b cell clones that secrete antibodies specific to antigen into the blood and antibodies bind to the antigens
    • Non-Specific
      • inflammation of the site
        • Vasodilation, More premeable blood vessels, Morre immune system cells brought to site of infection or infected tissue
      • Production of Interferons
        • Proteins that help prevent spread of virus to cells not  yet infected
          • By preventing viral synthesis, Activating specific and non-specific immune responses
      • Phagocytosis
        • Pathogens are digested by Macrophages/ Phagocytes, a phagocytic vacuole is formed
          • a lysosome fuses with the phagoytic vacuole and digestive enzymes are released breaking down the pathogen, 
            • the Phagocyte becomes an antigen presenting cell APC




A very good overview, thanks :)

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