genetic explanation for anorexia
- Created by: rachael.em
- Created on: 08-04-21 11:23
View mindmap
- Genetic explanations for AN
- AN results from an inherited predisposition
- evidence - increased risk for 1st degree relatives w/ disorder.
- Testing
- twin studies
- gene-profiling
- search for common genes between sufferers
- Holland (1988)
- twin study
- AN has a genetic basis
- other factors must be involved in AN otherwise, MZ would be 100%
- Strengths
- Bulik (2006) found an AN incidence (in 31,406 Swedish twin pairs) of 1.2% for females, 0.29% for males w/ heritability of disorder at 56%
- sig genetic influence in development of AN
- Scott-Van Zeeland et al (2014) found variants of EPHX2 gene, involved w/ cholesterol function in body, more common in those w/ AN
- findings suggest contributory role for genetic
- Bulik (2006) found an AN incidence (in 31,406 Swedish twin pairs) of 1.2% for females, 0.29% for males w/ heritability of disorder at 56%
- Weaknesses
- multiple genes involved + environmental factors, makes it diff to identify + quantify role of individual genes
- diff levels of influence on diff people.
- if genes solely responsible, concordance rates b/ween MZ twins would be 100%, but not
- suggests other factors involved - eg. nurture, neural etc
- multiple genes involved + environmental factors, makes it diff to identify + quantify role of individual genes
- genetics seen as only partly contributing - give level of inherited vulnerability
- when they develop AN dependent on presence of other factors, eg environmental stress
- AN results from an inherited predisposition
Comments
No comments have yet been made