Gene therapy
- Created by: vezting
- Created on: 23-02-16 17:54
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- Gene therapy
- the technique of molecular gene technology (gene therapy) can be used to treat some genetic disorders.
- somatic cell gene therapy
- as cells become specialised to a particular function some genes are swithced on or off
- some conditions are caused by inheritance of faulty alleles
- a functioning copy of the gene is inserted into cell(augmentation)
- cancers can be treated by elimintating certIain cells. they make cancerous cells express genes to produce proteins which lead to attack on immune system
- specific cells must be romoved, treated, then replaced.
- treatment is short lived.
- restriced to actual patient
- Germline cell gene therapy
- an engineered gene can be insteted into sperm egg or zygote.
- as the gamete grows every cell contains this engineered cells.
- the funtioning allele introduced into germline cells and is more straight forward than somatic
- cells derived from germilne all contain copy. passed on to offspring
- however it is unethical to engineer human embryos
- genetic manipulation could be passed on
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