Fever (Pyrexia)

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  • Created by: Aoife___
  • Created on: 17-10-22 23:22
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  • Fever (Pyrexia)
    • 1. Rise in body temperature above the normal i.e oral temperature (37.2oC)
    • 1.      Pyrogens a circulating protein – agent that produce a fever – can reset the thermostat in the hypothalamus & cause rise in body temperature
      • 2. Exogeneous pyrogens – derived from outside the host
        • 3. Endogeneous pyrogens –produced by individual
          • 4.    Pathogens, bacterial toxins & antigen-antibody complexes may act as pyrogens OR stimulate release of pyrogens by macrophages
    • Fever
  • Pyro = Heat
  • 3. Healing cells stop releasing chemicals
    • 4. Sweating = Vasodilation
  • 1. Injured cells start releasing chemicals
    • 2. Shivering = Vaso-constriction

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