DNA replication 

  • Created by: Ssbch3
  • Created on: 25-03-19 19:33
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  • DNA replication
    • Gyrase
      • Catalyses  untwisting of double helix shape
    • DNA helicase
      • Catalyses breaking of H bonds
      • Produces replication fork
    • DNA polymerase
      • Catalyses addition of nucleotides in 5’ to 3’ direction
    • DNA primase
    • Leading strand
      • Synthesised continuously
    • Lagging strand
      • In fragments, discontinuous
      • Goes in opposite direction of movement of replication fork
      • Short  segment produced is the Okazaki fragment
    • Addition of nucleotides
      • Free floating phosphonucle-otides bonded to exposed bases in original strands by complementar-y base pairing
        • Sugar-phosphate backbone

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