routes of drug administration
- Created by: ucnvrk2
- Created on: 05-10-17 13:12
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- Different Routes Of Drug Administration
- Enternal
- oral
- apply topically to the mouth
- swallow
- Via Gastrointestinal system
- Advantage
- Convinient, e.g painfree
- Goes along the whole GI track
- Cheap to make
- Disadvantage
- only insufficient amount absorbed
- passes throughthe liver (first pass effect)
- so broken down into other substances
- takes a long time
- some incapable of swalloing
- Advantage
- Via Gastrointestinal system
- sublingual
- placed unedr the tounge
- Advantage
- Quick
- Avoid first pass
- Disadvantage
- small quantity absorbed at a time
- Advantage
- placed unedr the tounge
- buccal
- Placed between gum and inner lining of cheek
- Advantage
- avoid first-pass effect
- Quick
- disadvantage
- small dosage
- inconvenient
- lost if swallowed
- Advantage
- Placed between gum and inner lining of cheek
- rectal
- oral
- Tropical
- administration of drug directly onto the skin surface
- Although it has a local effect it might not be able to get to the deeper layer of skin
- Includes mucous membrains
- E.g eyes, nose, ears, vagaina, colon, lungs, urethra
- Dosage form
- Skin
- cream
- Ointment
- lotions
- Patch
- Disk
- Eye/Ear
- soloutions
- Suspentions
- Ointments
- Nose/lungs
- sprays
- Powders
- Skin
- administration of drug directly onto the skin surface
- Parenternal
- Intravenous,(IV) administrated via injection, by passing the alimentary canal
- Advantage
- First pass avoided
- Bioavailbility 100%
- Large quantity
- Fast
- disadvantage
- Danger of infection
- Expensive
- Painful & less convinient
- Advantage
- inhalation
- Intramuscular(IM)
- Advantages
- first pass and gastric system avoided
- Rapid
- Disadvantage
- only a limited amount can be given
- Nerve damage
- Expensive
- Advantages
- Subcutaneous
- Injected under the skin, absorption is slow so action is prolonged
- e.g Implants
- Intra-arterial
- Rarely used is anticancer drugs for local effect
- intra-articular
- injection of antibiotics in inflamed joined cavities
- intradermal
- Drug given under the skin, that is painful
- Intravenous,(IV) administrated via injection, by passing the alimentary canal
- Enternal
- disadvantage
- Danger of infection
- Expensive
- Painful & less convinient
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