Cholera
- Created by: sarahbrennan98
- Created on: 12-04-15 10:01
View mindmap
- Cholera - cell structure and disease
- Plasma Membrane
- Controls the movement of substances in and out of a cell
- Plasmids
- small free-floating loops of DNA that contain genes for antibiotic resistance
- Capsule
- Made of saccharides, this layer of 'slime' protects the cell from attacks by the immune system
- Cell Wall
- Made up of peptidoglycan the cell wall offers support to the cells structure
- How does it work?
- Cholera uses a toxin that makes the chloride ion protein channel open within the small intestine
- The chloride ions then enter the lumen of the small intestine, thus decreasing the water potential
- This causes a concentration gradient, so the water from the blood moves into the intestine lumen and causes diarrhoea
- Diarrhoea causes massive amounts of dehydration in the body, this is easily treatable but if left untreated it can be fatal
- This causes a concentration gradient, so the water from the blood moves into the intestine lumen and causes diarrhoea
- The chloride ions then enter the lumen of the small intestine, thus decreasing the water potential
- Cholera uses a toxin that makes the chloride ion protein channel open within the small intestine
- DNA
- Long, free-floating coil of DNA in cytoplasm
- Flagellum
- Allows the cell to move by rotating its hair-like structure
- How is it treated?
- Oral Re-hydration Solutions (ORS)
- Theses contain Na ions, Cl ions, Glucose and sucrose, all of which is dissolved in water
- Na and Glucose are co-transported, this is because Na helps the body absorb glucose faster
- ORS balances the concentration gradient to prevent more water entering the lumen
- This is a cheap, but effective way of beating Cholera but in 3rd world countries this can still be hard to find
- ORS balances the concentration gradient to prevent more water entering the lumen
- Na and Glucose are co-transported, this is because Na helps the body absorb glucose faster
- Ethical Issues
- The most affected are children whose parents put them in for ORS drug trials
- people are given different treatments in bind trial, but some think that they should get to decide what treatment they get
- New drugs aren't always successful, so some patients are at risk of death
- Theses contain Na ions, Cl ions, Glucose and sucrose, all of which is dissolved in water
- Oral Re-hydration Solutions (ORS)
- Plasma Membrane
Comments
No comments have yet been made