Biological Therapies

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  • Biological Therapies
    • Drug Therapy
      • Anti-depressants reduce symptoms of mood disorders
        • MOAIs (monoamine oxidase inhibitors)
          • Block the action of the enzyme that breaks down serotonin, so increase it's availability in nervous system
        • SSRIs (selective serotonin re-uptake inhibitors)
          • Block the re-uptake of serotonin by the sending neuron, making more of it available in the synapse
        • TCAs (tricyclics)
          • Block the reabsorption of serotonin and adrenaline  into the nerve cells
      • Anti-psychotics reduce severe symptoms for disorders like scizoprehnia
        • Major tranquilizers like pheno-thiazines which sedate and alleviate symptons (hallucination and delusions) and block the D2 receptor for dopamine
    • ECT (electrocon-vulsive therapy)
      • Course of 6-12 treatments where anti-depressants have been ineffective
      • Patient lies on the bed and is given anaesthetic and muscle relaxant
      • Current of 70-130 volts passed through one half of brain  (non-dominant hemisphere to prevent memory loss) via electrodes
      • Causes a 1-2 minute seizure - thought to be therapeutic part as it re-sets brain chemistry


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