Biological Therapies for OCD
- Created by: daisygbates
- Created on: 29-01-16 13:59
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- Biological Therapies for OCD
- Psychosurgery
- Cingulotomy
- Removes cingulum (links orbitofrontal cortex to caudate nucleus)
- Capsulotomy
- Removes capsule (involved with emotion and anxiety)
- Brain surgery
- Usually last resort due to high risks
- 45% patients partly improved after cingulotomy
- Jung et al found similar recovery rate
- Does surgery remove symptoms, or reduce motivation and energy?
- Mary Lou Zimmerman
- Severe OCD
- Both cingulotomy and capsulotomy
- Left unable to walk, stand, eat by herself
- Cingulotomy
- Chemotherapy
- Anti-anxiety drugs
- Benzodiazepines
- Slow down nervous system by enhancing GABA effect
- Benzodiazepines
- Antidepressants
- SSRIs
- Increases serotonin levels (low serotonin associated with OCD)
- Tricyclics
- Increase serotonin and noradrenaline levels
- More effective than SSRIs, less prescribed due to side effects
- SSRIs
- Side effects
- Easy to take and prescribe
- Effective and better than placebos
- Only treat symptoms, not cause?
- Anti-anxiety drugs
- Approach is reductionist
- Assumes simple link between OCD and biology
- Psychosurgery
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