6. Thyrotropin-releasing hormone (TRH) from hypothalamus, goes to what from anterior pituitary (thyrotroph cells)?
Thyroid-stimulating hormone (TSH)
Follicle-stimulating hormone (FSH)
Human growth hormone (hGH)
7. T3 & T4 cause: select incorrect answer
↑ Use of glucose for ATP production
↑ Metabolic rate
↑ K+ reuptake
↑ Breakdown of fats
↑ Protein synthesis
8. Hypothyroidism can be treated with
T2
T4
T3
9. Treatment of hyperthyroidism: select wrong answer
ANTITHYROID DRUGS
CBTherapy
2 regimes: “titration” (18 months) or “block and replace” (6 months)
Block conversion of T4 to T3 (propylthiouracil) and Block TGB synthesis
10. thyroid hormones have what effect on carbohydrates - uptake from GI tract
increase
decrease
11. Thyroid hormones are controlled via?
pituitary and hypothalamus
ANS and hypothalamus
pituitary and ANS
12. what is the thyroid gland able to secrete from the blood stream
calcium
iodine
potassium
sodium
13. what deficiency is Goitre?
calcium
iodine
hGH
thyroid hormone
14. location of thyroid
attached to thymus
attached to larynx
posterior to thymus
superior to thymus
15. Production of Thyroid Hormone, what happens to tyrosine in colloid?
Follicularisation
Iodination
Proliferation
16. longer half life in blood?
T4
T3
17. Production of Thyroid Hormone, what Trap iodide, active, against steep concn grad
Na+/I- symporter (NIS) and I-/Cl- porter (pendrin, PDS)
Synthesise glycoprotein thyroglobulin (TGB)
Release TGB into colloid
follicular cells
thyroid glands
GPCRs
18. effect of Administration of thyroid hormones on BASAL METABOLIC RATE (BMR) in adults