A protease enzyme that enters the small intestine and is converted to its active form by enterokinase. It can then activate other inactive zymogens (11)
Acid secretion only occurs whilst we're eating, otherwise parietal cells are in inactive form. When there is stimulation, its tubulovesicles merge together to produce canaliculi which increases their surface area, ready for acid secretion (4, 9)
Secreted by D cells - it inhibits acid secretion from parietal cells (12)
Secreted by parietal cells - helps to absorb vitamin B12 from the ileum more easily. Vit B12 is essential for the maturation of RBC. You can otherwise end up with premicious anaemia (9, 6)
The presence of large amounts of HCO3- in the bloodstream after eating means that (theoretically) it would completely neutralise the acid and remain in excess, rendering the blood alkaline. However, this is counteracted. (8, 4)
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