Secretions of the Stomach and Pancreas

Across

• 1. Secreted by parietal cells - it allows for a sterile environment; it produces pepsinogen which is converted to pepsin to allow for the partial digestion of proteins before they go to the small intestine; it converts Fe3+ to Fe2+ for easier absorption (4)
• 4. Secreted by surface goblet cells and mucous neck cells - it neutralises acid in the lining of the stomach to prevent corrosion to the stomach wall by gastric acid (6)
• 5. A stimuli of parietal cells - Gastrin hormone is released from the stomach into the bloodstream; it eventually goes back to act on the parietal cells, this causes a greater effect (9)
• 6. A stimuli of parietal cells - The vagus nerve can release the neurotransmitter acetylcholine to signal to the parietal cells to produce acid (9)
• 7. Second phase of acid secretion. Food enters the stomach, causing stretching/distension which is detected by pressure receptors. This causes ACh release. The breakdown of proteins into peptides and amino acids stimulate gastrin release (7)
• 10. A protease enzyme that enters the small intestine and is converted to its active form by enterokinase. It can then activate other inactive zymogens (11)