Finnish Adoption study. All separated from their mother by 4yrs. 7% of Offspring with SXmother (112cases )developed SX, Control group (135)-1.5% developed SX
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Card 7
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Administered amphetamines to a group of rats. Dopamine levels were increased. Schizophrenic-like symptoms appeared.
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Card 8
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Used post-mortem examinations of schizophrenics and found higher density of dopamine receptors in the brain, compared to mentally healthy people.
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Card 9
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Repeated Owens study and found similar findings.
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Card 10
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Those with Parkinson’s disease have low dopamine levels. It was found that L-dopa raised dopamine levels but also induced SX symptoms. Concludes that high dopamine levels = SX symptoms.
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Card 11
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SX patients have enlarged ventricles in their brains. However there is no established cause and effect.
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Card 12
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SX patients have less activity in the frontal lobes when performing cognitive tasks.
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Card 13
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164 adopted children from Finland, biological mothers had SX. 67% later diagnosed with SX, only 2% in control group.
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Card 14
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Meta-analysis of ALL twin SX studies pre-2001. 40.4% concordance rate for MZ twins. 7.2% for DZ twins.
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Card 15
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Higher Risk of SX offspring from mothers suffering toxoplasmosis compared o control group.