6. Who found that amphetamines increase dopamine, and therefore increase negative symptoms? (Supporting evidence for DH)
Brown et al
Tienari et al
Curran et al
Howes et al
7. How is the biological explanation of schizophrenia reductionist?
It ignores the psychodynamic approach
There is clear evidence that environmental factors affect the development of schizophrenia
It ignores the cognitive approach
There is clear evidence that biological factors are the most important
8. What is hyperdopaminergia?
An abnormally high level of dopamine in the subcortex
An abnormally low level of dopamine in the cortex
9. Who theorised hypodopaminergia?
Gottesman
Davis et al
Ripke et al
Brown et al
10. Is schizophrenia aetiologically heterogeneous?
Yes
No
11. What can mutation in parental DNA NOT be caused by?
Allergies
Viral infection
Radiation
Poison
12. How many gene variations did Ripke find that may cause schizophrenia in his meta-analysis?
93
20
108
258
13. Who found that biological children of schizophrenics are more likely to develop the disorder, even when adopted by non-schizophrenics? (Supporting evidence)
Ripke et al
Gottesman
Tienari et al
Curran et al
14. The most likely genes to code for schizophrenia also code for what?
Neurotransmitters
Hormones
15. Is dopamine the only neurotransmitter linked to schizophrenia?
No - glutamate is linked too
Yes - dopamine is the only one
16. Is schizophrenia polygenic or pleiotropic?
Polygenic
Pleiotropic
17. Does schizophrenia have candidate genes that code for it?
Yes
No
18. What is hypodopaminergia?
An abnormally low level of dopamine in the cortex
An abnormally high level of dopamine in the subcortex
