S2W11 How do we decide what drugs we can afford? - DH

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What is the aim of the NICE technology appraisal?
To review the clinical and economic evidence, and then make recommendations on the appropriate use of both new and existing medicines
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What are the three stages of the NICE technology appraisal assessment process for new drugs?
Scoping phase
Assessment phase
Appraisal phase
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What is the scoping phase?
Determines which diseases and patient groups to consider and which existing drugs to compare the new drug against
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What is the assessment phase?
Evaluates evidence of the drugs clinical and cost effectiveness
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What is the appraisal phase?
An appraisal committee reaches a decision on whether the NHS should fund the new drug, based on factors including:
- strength of clinical evidence
- degree of clinical need among patients
- cost-effectiveness of the drug given its proposed price
- robustn
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What is effectiveness?
Measure of improvement in clinicaloutcomes from an intervention
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What is cost-effectiveness?
Measure of improvement in clinical outcomes from an intervention relative to the cost of the intervention
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What is QALY?
Quality-adjusted life years
A generic measure of disease burden, including both the quality and the length of life
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What is ICER?
Incremental cost-effectiveness ratio
Measure of improvement in clinical outcomes from an intervention relatie to the cost of the intervention - compared to current best/standard treatment
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What is the equation for ICER?
Difference i cost divided by the difference in effect (£/QALY)
The lower the value, the more the cost effectiveness
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What are the 5 dimensions (5D) of EQ-5D-3L?
mobility
self-care
usual activities
pain/discomfort
anxiety/depression
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What are the 3 levels (3L) of EQ-5D-3L?
I have no problems
I have some problems
I was unable to...
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Card 2

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What are the three stages of the NICE technology appraisal assessment process for new drugs?

Back

Scoping phase
Assessment phase
Appraisal phase

Card 3

Front

What is the scoping phase?

Back

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Card 4

Front

What is the assessment phase?

Back

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Card 5

Front

What is the appraisal phase?

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