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6. Glomerular filtration is significantly more efficient than tubular secretion in the elimination of drugs

  • False
  • True

7. Which of the following is not a route of administration of a drug?

  • Intravenous
  • Intramuscular
  • Transdermal
  • Subcutaneous
  • Inhalation
  • Percutaneous
  • Intranasal
  • Oral
  • Rectal
  • Excretion
  • Sublingual
  • Buccal

8. What is the definition of bioavailability?

  • Proportion of drug administered that reaches systemic circulation
  • Duration taken for drug concentration to fall to half its original concentration
  • Metabolism by conjugation reactions, enabling prolonged stay of drugs in body
  • Process of albumin attachment, which does not allow for glomerular filtration in renal excretion

9. Which of the following does not correlate with the term 'lung excretion'?

  • Gas exchange via passive diffusion
  • Gas exchange occurs between circulation and alveoli
  • Excreted by inspiration
  • Excreted by expiration

10. What is Biotransformation?

  • Where a drug is bound to a plasma protein, enabling drug absorption
  • Where an inactive precursor becomes an effective metabolite
  • The ability for a drug to become crystalline
  • None of the above

11. What is Pharmacokinetics?

  • The effect the route of administration has on the drug
  • The effect of the body on a drug
  • The effect of a drug on the body
  • The mechanism of drug elimination

12. Which of the following is: Initially giving a patient a large dose, which is then adjusted with treatment

  • Half life
  • Loading dose
  • (AUC Oral / AUC IV) x 100
  • Steady State

13. Chloramphenicol is metabolized through conjugation reactions

  • True
  • False

14. What method is best for the elimination of a drug in acute intoxication?

  • Biotransformation
  • Milk/plasma indicators
  • Haemodialysis
  • Enterohepatic cycle

15. Which of the following is: The percentage of administered drug that reaches systemic circulation

  • Loading dose
  • Half life
  • (AUC Oral / AUC IV) x 100
  • Steady State