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6. Glomerular filtration is significantly more efficient than tubular secretion in the elimination of drugs
7. Which of the following is not a route of administration of a drug?
- Intravenous
- Intramuscular
- Transdermal
- Subcutaneous
- Inhalation
- Percutaneous
- Intranasal
- Oral
- Rectal
- Excretion
- Sublingual
- Buccal
8. What is the definition of bioavailability?
- Proportion of drug administered that reaches systemic circulation
- Duration taken for drug concentration to fall to half its original concentration
- Metabolism by conjugation reactions, enabling prolonged stay of drugs in body
- Process of albumin attachment, which does not allow for glomerular filtration in renal excretion
9. Which of the following does not correlate with the term 'lung excretion'?
- Gas exchange via passive diffusion
- Gas exchange occurs between circulation and alveoli
- Excreted by inspiration
- Excreted by expiration
10. What is Biotransformation?
- Where a drug is bound to a plasma protein, enabling drug absorption
- Where an inactive precursor becomes an effective metabolite
- The ability for a drug to become crystalline
- None of the above
11. What is Pharmacokinetics?
- The effect the route of administration has on the drug
- The effect of the body on a drug
- The effect of a drug on the body
- The mechanism of drug elimination
12. Which of the following is: Initially giving a patient a large dose, which is then adjusted with treatment
- Half life
- Loading dose
- (AUC Oral / AUC IV) x 100
- Steady State
13. Chloramphenicol is metabolized through conjugation reactions
14. What method is best for the elimination of a drug in acute intoxication?
- Biotransformation
- Milk/plasma indicators
- Haemodialysis
- Enterohepatic cycle
15. Which of the following is: The percentage of administered drug that reaches systemic circulation
- Loading dose
- Half life
- (AUC Oral / AUC IV) x 100
- Steady State