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6. Which statement best describes partial agonists?

  • Drugs that bind to and activate a given receptor, but have only partial efficiency at the receptor relative to a full agonist
  • A drug that causes as opposing biological response to another drug upon activation of the cell receptor
  • Drugs that blocks the actions of another drug, had it activated the cell receptor
  • Causes an action opposite to that of the agonist

7. What information is false about EC50 values?

  • A drug with a higher EC50 value is worse than a drug with a lower EC50 value
  • The potency of a drug can be observed on a curve where the EC50 value is lower than another drug for the same function
  • Concentration of a drug that gives half maximum pharmaceutical response
  • A drug with a lower EC50 value is worse than a drug with a higher EC50 value

8. Which description best suits: Inverse agonist

  • A drug that causes as opposing biological response to another drug upon activation of the cell receptor
  • A drug that activates a receptor, resulting in a biological response
  • A drug that activates a receptor, resulting in a lower biological response than another which would result in higher efficacy
  • A drug that blocks the actions of another drug, had it activated the cell receptor

9. Which statement best describes the Emax value?

  • Drug that acts competitively and irreversibly to block the actions of another drug on the same active site
  • Maximum effect at high drug concentrations when all the receptors are occupied by the drug
  • Drugs that bind to and activate a given receptor, but have only partial efficiency at the receptor relative to a full agonist
  • Comparison between the amount of therapeutic agent that causes the therapeutic effect to the amount that causes toxicity

10. Which of the following is the most accurate application for drug interaction in pharmacodynamics

  • All of the above
  • Intracellular/nuclear receptors
  • Channel linked receptors and enzyme linked receptors
  • G protein coupled receptors and enzyme receptors

11. Which drug would be the best choice for therapy in the options presented?

  • Drug D: Identical specifications to drug B with severe contraindications
  • Drug B: High EC50 and low Emax compared to the other drugs
  • Drug C: Identical specification to drug A with mild contraindications
  • Drug A: Low EC50 and high Emax compared to the other drugs