Pharmaceutical Semi-solids 0.0 / 5 ? PharmacySemi-solidsUniversityNone Created by: SamDaviesCreated on: 15-04-18 16:59 10248369751 Across 1. Produced by emulsifying agents of natural origins, like beeswax, wood alcohols/fat. Provide an oily barrier that reduces water loss from the stratum corneum. Good emollient properties. (5, 2, 3, 5) 6. Heat reversible gels held together by weak hydrogen bonds (4, 3) 8. A semi-solid preparation in which a liquid phase is constrained within a 3D polymeric matrix having a high degree of physical or chemical crosslinking. They have a high water content and the drugs can be suspended in the matrix or dissolved in liquid (4) 9. A semi-solid preparation that contains a high percentage (up to 50% w/w) of insoluble powders in a fatty base. The high amount of particulate matter makes it stiff. (6) Down 2. An example of an oleaginous fatty base of suppositories, alongside synthetic triglyceride mixtures. Fatty bases are preferred for rectal administration due to emollient properties (9, 3) 3. Irreversible gel system made of covalent bonds (4, 3) 4. Examples of natural gums that are found within the liquid phase of gels (6, 4) 5. An example of a fatty paste (4, 5) 7. Viscous semi-solid emulsions which contain excess emulsifier. There are other components at the droplet surface which produce a semi-solid multiphase. This ensures the disperse phase is at a distance, not interfacial films (5) 10. Transparent or translucent non-greasy semi-solid gels. Some are as transparent as water, others are turbid because the colloidal aggregates disperse light (7)
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