“DOPA decarboxylase” also converts L-DOPA into dopamine in the periphery, hence reducing the amount of L-DOPA available to cross the BBB. What can be done to solve this?
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Card 17
Front
Why would you want a drug not to enter the CNS?
Back
Card 18
Front
What is the function of the placenta?
Back
Card 19
Front
Describe other other membrane barriers that can cause problems for drug distribution
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Card 20
Front
Name 2 binding proteins in the blood?
Back
Card 21
Front
Why can't bound drugs be active?
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Card 22
Front
Why does binding to plasma proteins lead to drug-drug interactions?
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Card 23
Front
Give an example of a drug-drug interaction
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Card 24
Front
Unbound drugs are inactive. True or false?
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Card 25
Front
Many drugs bind reversibly to proteins within tissue. What does this lead to?
