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1. how do 5-HT agonists reduce anxiety
- increase amount of 5-HT released
- activation of 5-HT neurons releases behavioural inhibition
- destruction of 5-HT neurons releases behavioural inhibition
- chemicals released from 5-HT neurons release behavioural inhibition
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2. Which mucoactive breaks disulphide bonds linking mucin polymers
- Mucokinetics
- Expectorants
- Mucolytics
- Mucoregulators
3. DMARDs - What is the mechanism of action of sulphasalazine
- inhibit COX-1 only
- IL1 inhibition and prevention of collagen maturation
- COX inhibitor and 5 aminosalicyclic acid scavenges radical oxygen metabolites
- inhibit toll like receptors and antigen processing
4. Antimicrobials - what do macrolides do
- interfere with RNA transcription
- prevents translation
- bind to 50s subunit
- bind to 70s subunit
5. What do fusion inhibitors do to treat HIV
- inhibit fusion of viral cell wall and cellular membranes
- inhibit fusion of viral and cellular membranes
- prevent entry for virus by blocking pores on membrane
- puncture viral membrane so fusion cannot occur
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