Osmo Regulation

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  • Created by: Om4r
  • Created on: 30-05-19 16:08
What does ADH stand for?
Antidiuretic hormone
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What is ADH?
A hormone that controls the permeability of the collecting duct walls
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What is an Osmoreceptor?
A sensory receptor that detects changes in water potential
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What is Osmoregulation?
The control of the water potential in the body
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What does Osmoregulation involve?
Controlling levels of both water and salt in the body
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What must osmoregulation occur?
To prevent water entering the cells and causing lysis or leaving cells and causing crenation
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What 3 sources does the body gain water from?
Food, drink and metabolism
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How is water lost from the body?
In urine, sweat, faeces and water vapour exhaled in air
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What organ is responsible for osmoregulation?
The Kidney
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How does the Kidney alter the volume of Urine produced?
By altering the permeability of collecting ducts
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What occurs if the body needs to conserve less water?
Walls of collecting duct become less permeable, less water is reabsorbed and there's a greater volume of urine
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What occurs if the body needs to conserve more water?
Walls of collecting duct become more permeable, more water is reabsorbed into blood, smaller volume of urine produced
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What controls the permeability of the collecting duct?
ADH
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What do the cells in the walls of the collecting duct have that allow ADH bind?
Cells in the walls of the collecting duct have membrane bound receptors for ADH
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What is the First stage for ADH to increase the permeability of the collecting duct?
ADH binds to the receptors causing a chain of enzyme controlled reactions
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What effect does the binding of ADH to receptors have?
Leads to vesicles containing aquaporins to fuse with the cell surface membrane making walls more permeable to water
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What occurs when the body is hydrated ?
ADH levels fall, cell surface membrane folds inwards (invaginates) creating new vesicles that remove the aquaporins from the membrane
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Where are osmoreceptors found?
In the Hypothalamus
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What do osmoreceptors respond to?
The effects of osmosis
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What happens to osmoreceptors when the water potential of blood is low?
The osmoreceptor cells lose water by osmosis and shrink
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What occurs as a result of osmoreceptors shrinking?
Stimulates neurosecretory cells in the Hypothalamus
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Where is ADH manufactured?
In the cell body of neurosecretory cells in the hypothalamus
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What happens when ADH is produced?
They release ADH, it moves down the axon to the terminal bulb in the posterior pituitary gland where it's stored in vesicles
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What happens when neurosecretory cells are stimulated by osmorecpetors?
Neurosecretory cells carry action potentials down their axons and cause the release of ADH by exocytosis
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What happens once the water potential of the blood rises again?
Less ADH is released and ADH is slowly broken down
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Other cards in this set

Card 2

Front

What is ADH?

Back

A hormone that controls the permeability of the collecting duct walls

Card 3

Front

What is an Osmoreceptor?

Back

Preview of the front of card 3

Card 4

Front

What is Osmoregulation?

Back

Preview of the front of card 4

Card 5

Front

What does Osmoregulation involve?

Back

Preview of the front of card 5
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