Back to quiz

6. How does Ras stabilise Myc

  • phosphorylation of S62 and T58
  • dephosphorylation of S62 and T58

7. How does AKT/PKB bind PIP3

  • via PH domain
  • Via kinase domain
  • Via SH2 domain

8. How do Myc and RAS cooperate

  • Ras overcomes Myc induced apoptosis and Myc overcomes RAS induces senescence
  • Myc overcomes Ras induced apoptosis and RAs overcomes Myc induces senescence

9. Residue of regulatory Tryosine in SRC kinase

  • Y527
  • Y416

10. Residue of activatory Tryosine in SRC kinase

  • Y416
  • Y527

11. Myc does not do what

  • promote angiogenesis
  • promote immune response
  • Promote stromal remodelling
  • Promote senescence
  • promote invasion

12. SH2 domain recognises what

  • Phosphorylated Tryosines
  • Proline rich region

13. Tamoxifen mouse allows what

  • controlled expression of Myc
  • consituative myc expression

14. PI3K has what domains

  • P110 (catalytic) and P85 (regulatory)
  • P110 (regulatory) and P85 (catalytic)