6. How does Ras stabilise Myc
- phosphorylation of S62 and T58
- dephosphorylation of S62 and T58
7. How does AKT/PKB bind PIP3
- via PH domain
- Via kinase domain
- Via SH2 domain
8. How do Myc and RAS cooperate
- Ras overcomes Myc induced apoptosis and Myc overcomes RAS induces senescence
- Myc overcomes Ras induced apoptosis and RAs overcomes Myc induces senescence
9. Residue of regulatory Tryosine in SRC kinase
- Y527
- Y416
10. Residue of activatory Tryosine in SRC kinase
- Y416
- Y527
11. Myc does not do what
- promote angiogenesis
- promote immune response
- Promote stromal remodelling
- Promote senescence
- promote invasion
12. SH2 domain recognises what
- Phosphorylated Tryosines
- Proline rich region
13. Tamoxifen mouse allows what
- controlled expression of Myc
- consituative myc expression
14. PI3K has what domains
- P110 (catalytic) and P85 (regulatory)
- P110 (regulatory) and P85 (catalytic)