Narcolepsy

Across

• 1. Lin et al found narcoleptic dogs had a ________ in a gene which disrupted the way hypocretin was processed. Hypocretin is thought to play a role in maintaining wakefulness. (8)
• 5. Vogel found that ___ sleep occurred at the onset of sleep in narcoleptics. This explains the loss of muscle tone and hallucinations. (3)
• 6. Honda et al found an increased frequency of one type of human _________ antigen (HLA). They coordinate the immune system response and are found on the surface of white blood cells. (9)
• 9. Sufferers experience sudden and uncontrollable attacks of _____. (5)