165 new antibiotic resistant infections per day. High rate of bloodstream infections. Increase in E.coli and Klebsiella pneumonia. Reduced S. Aureus. 30 day all cause fatality higher for antibiotic resistant compared to antibiotic susceptible BSIs
E.coli (most common cause). Young children and elderly most at risk. AMR detected in hospitals compared to community. Rapid increased use of cephalosporin and quinolone antibiotics. Linked with increased resistance detected in E.coli - graphs/data
3 of 9
State the issues with urinary-tract infections
Majority of cases caused by E.coli. Nitrofurantoin use doesn't lead to changes in proportion of resistance detected (despite increased use). Antibiotic resistance increased with age (graph)
4 of 9
What is the issue with carbapenemase-producing organisms?
Increase in detections from bacteria but low numbers of BSIs with carbapenemase producing Gram negative bacteria identified - graph
5 of 9
State features of antimicrobial consumption data - headlines
Antibiotic consumption increasing. Reductions occurred in general and dental practice. Increases seen in other community and hospital settings (graphs/data)
6 of 9
State features of antimicrobial use in hospitals
Increase in antimicrobial use. Now stopped and consumption is being reduced in hospitals. Financial incentives in place to change antimicrobial prescribing (data). Local/national data, AMR local indicators (fingertips), GSTT consumption data
7 of 9
What are the conclusions made about antimicrobial use? (1)
AMR increasing in England (Gram negative, reduction in Gram positive). E.coli bloodstream infections increasing/resistance. Resistance rates to trimethoprim and nitrofurantoin stable. CRO numbers increasing (but low BSI numbers)
8 of 9
What are the conclusions made about antimicrobial use? (2)
Consumption in primary/secondary care is changing. Certain classes increasing (concerns/potential consequences). Comparison of hospitals (AMR local indicators)
Comments
No comments have yet been made