Infection

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What is wound healing?
The body responds to an insult, be it an injury, incision, infection or implant.
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What are the four stages of tissue injury?
hemostasis,
inflammation,
proliferation,
remodeling
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What is the purpose of the haemostasis (day 1) stage?
prevent blood loss and limit damage by encouraging immobilisation
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What is the purpose of the acute inflammation (day 1 - 4) stage?
white blood cells (leucocytes) defend the area
promotes repair of injured tissue
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What are the 5 cardinal signs of acute inflammation?
pain, warmth, swelling, redness and loss of function
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How does bone tissue remodel?
complete remodelling (regeneration)
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How does skin tissue remodel?
nearly complete
can be absence hair follicles or scarring at injury site
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How does articular cartilage repair?
avascular ( temporary or permanent loss of blood supply to the bone) so limited ability to repair or regenerate
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What happens at the proliferation (day 4 - 21) stage?
increase in resident cell number, secretion of new tissue matrix (granulation tissue formed and recovers structure and function of wounded skin).
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What happens at the remodelling (day 21 - 2 yrs) stage?
remodelling of the granulation tissue by breakdown of collagen and replacement with functional tissue.
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What factors impact on the success at the remodelling stage?
degrees of injury,
tissue type,
patient factors
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Other cards in this set

Card 2

Front

What are the four stages of tissue injury?

Back

hemostasis,
inflammation,
proliferation,
remodeling

Card 3

Front

What is the purpose of the haemostasis (day 1) stage?

Back

Preview of the front of card 3

Card 4

Front

What is the purpose of the acute inflammation (day 1 - 4) stage?

Back

Preview of the front of card 4

Card 5

Front

What are the 5 cardinal signs of acute inflammation?

Back

Preview of the front of card 5
View more cards

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