Genetic Explanation of Schizophrenia

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outline the belief of the explanation
believes there is a link between genes and an individuals susceptibility to schizophrenia
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how close does a relative have to be to you?
the closer the relative, the more likely you will develop schizphrenia e.g. more likely if affected relative is your mum instead of your aunt
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is it just one gene?
no. it is more likely a combination of genes but even if you have that exact combination it doesn't necessarily mean that schizophrenia will be developed in the individual
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genetic mutation
it is said that types of genetic mutation must be present in order for the individual to develop schizophrenia and these mutations can cause critical neural pathways to be disrupted which actually causes schizophrenia
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dopamine
explains the dopamine hypothesis by saying that the excess production of dopamine is genetically transferred through generations
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STRENGTH: gottesman
50% concordance rate for monozygotic twins but only 15% for dizygotic twins
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STRENGTH: kety et al
found that higher concordance for biological relatives than adoptive relatives
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STRENGTH: tries to explain
tries to explain why there isn't an 100% concordance rate because says that genetic mutations must disrupt the critical neural pathways in order for schizophrenia to be developed
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WEAKNESS: mimic
certain psychologists say that there are concordance rates simply because family members mimic the schizophrenic symptoms
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WEAKNESS: not 100%
the concordance rates are not 100% which suggests that there are other causes of schizophrenia alongside genetics
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WEAKNESS: sample
very small sample size for twin studies which means the generalisability of the results is low
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Card 2

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how close does a relative have to be to you?

Back

the closer the relative, the more likely you will develop schizphrenia e.g. more likely if affected relative is your mum instead of your aunt

Card 3

Front

is it just one gene?

Back

Preview of the front of card 3

Card 4

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genetic mutation

Back

Preview of the front of card 4

Card 5

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dopamine

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