Endogenous Pacemakers and Exogenous Zeitgebers

?
2 Endogenous?
SCN & Pineal gland
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Where is the SCN?
Hypothalamus
2 of 17
What ensures that all biological clocks receive correctly timed co-ordinated signals?
Spontaneous synchronicity of SCN neurones
3 of 17
What brain regions does it link?
Those that control sleep and arousal
4 of 17
Changes in external light?
Info about the changes are sent along the optic nerve to the SCN
5 of 17
What does it regulate?
The manufacture and secretion of serotonin
6 of 17
What does the pineal gland release?
Melatonin
7 of 17
What does this hormone do?
Inhibits brain mechanisms that promote wake (therefore increases at night)
8 of 17
2 types of exogenous?
Light and social cues
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What detects light intensity in the eyes?
Photoreceptors
10 of 17
How is the sleep wake cycle maintained in blind ppl?
Connections between eye & SNC still present (so still influenced by light)
11 of 17
What do social cues compensate for?
A lack of natural zeitgebers (e.g. meal times)
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Animal studies
Bred hamsters with 20 hr CR, implanted SCN neurones in health hamsters, CR also extended to 20 hrs
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Separate rhythms
Aldcroft - 25 dears with no access to zeitgebers = core body temp maintained 24 hr cycle / sleep wake increased to 30 hrs
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Jet lag
Pps exposed to continuous bright light - CR shifted back 2.1 hours = so exposure to bright before tale to decrease readjustment time?
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Artificial light
Ppl working under normal 'warm' light = synchronisation to natural sunrise on days off / blue enriched light = office hours on free days
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Therefore what does this suggest?
Light is the dominant zeitgeber
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Other cards in this set

Card 2

Front

Where is the SCN?

Back

Hypothalamus

Card 3

Front

What ensures that all biological clocks receive correctly timed co-ordinated signals?

Back

Preview of the front of card 3

Card 4

Front

What brain regions does it link?

Back

Preview of the front of card 4

Card 5

Front

Changes in external light?

Back

Preview of the front of card 5
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