pre discovery, target ID, target validation, drug discovery, early safety tests, lead optimization
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pre discovery
research is done regarding the disease- need to understand the disease and its cause
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Target ID
a molecule is identified which is involved in the disease
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target vailidation
the role of the target is confirmed. checking the target influences the progression of the disease. This is a crucial step to ensure projects do not lead to dead ends and money wastage
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Drug discovery
search for drug which will act on the target.
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Early safety tests
tests carried out on cells and animals to test ADME
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Lead optimization
Lead drug candidates are altered slightly to improve properties
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Pre clinical trials
carried out on animals to ensure safe for human testing
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