Drug action and introduction to structure-activity relationships 0.0 / 5 ? PharmacyPH1122UniversityNone Created by: EmmanuelakyeCreated on: 12-02-20 14:30 how are functional groups formed clusters of atoms within a molecule form this 1 of 24 examples of things a drug can bond to in its environment water, drug target, biological membrane 2 of 24 what is the principle of complentarity that adenine will only ever bond to thymine and guanine to adenine 3 of 24 what do functional groups need for complementarity an appropriate reactivity and arrangement of atoms in space 4 of 24 what does acetylcolinesterase do hydrolyses acetylcholine 5 of 24 how many spatial coordinates are needed to map an atom 3 6 of 24 what is the role of adrenaline Stimulates sympathetic nervous system, Causes vasoconstriction 7 of 24 what type of protein does adrenaline act on g-protein coupled receptor 8 of 24 what functional groups are involved in D-(-)-adrenaline amino, catechol ring and side chain hydroxyl 9 of 24 what is the iupac of a catechol group 1,2-dihydroxybenzene 10 of 24 what kind of enantiomer is D-(-)-adrenaline r 11 of 24 what kind of enantiomer is L-(+)-adrenaline s 12 of 24 define pressor constricting blood vessels to increase blood pressure 13 of 24 is L-(+)-adrenaline a strong or weak pressor weak pressor 14 of 24 what do many target molecules react to more than 1 structure of drug 15 of 24 what can be understood if properties of the drugs are understood pharmacological behaviour of the drug and better rational choices in therapy 16 of 24 what is the function of etoposide blocks Topoisomerase II 17 of 24 side effects of etoposide can cause hypersensitivity 18 of 24 function of doxorubicin inhibits topoisomerase II, binds to DNA-enzyme complex, DNA is cut and inhibits resealing 19 of 24 what is α- and β- tubulin proteins which are the main consituent of microtubules 20 of 24 what does vincristine bind to α- and β- tubulin 21 of 24 what is an antimitotic halt cell division by inhibiting polymerization 22 of 24 what is the side effect of vincristine causes blistering ( is a vesicant) 23 of 24 what type of target do most drugs act on protein 24 of 24
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