6. CFTR regulates conductance of which other ion channel in epithelial membrane? INHIBITS
EKC ( epithelium potassium channel)
ENaC ( epithelium sodium channel)
ECaC ( epithelium calcium channel)
7. Activation of CFTR chloride channel activity by
what receptors
alpha 2-adrenergic receptors
alpha 1 -adrenergic receptors
B2-adrenergic receptors
B1-adrenergic receptors
8. what else is found bound to Erin?
cAMP
PKA
PKD
9. CFTR consists of: select correct answer
CFTR consists of two transmembrane domains (TM1 and TM2), three nucleotide binding domains (NBD1, NBD2 and NBD3), and a unique intracellular hydrophilic regulatory (R ) domain.
CFTR consists of two transmembrane domains (TM1 and TM2), two nucleotide binding domains (NBD1 and NBD2), and a unique intracellular hydrophilic regulatory (R ) domain.
CFTR consists of three transmembrane domains (TM1, TM2, TM3), two nucleotide binding domains (NBD1 and NBD2), and a unique intracellular hydrophilic regulatory (R ) domain.
10. MANY ORGANS ARE AFFECTED BY CF: SELECT INCORRECT ONE
SMALL INTESTINE
BRAIN
SKIN
PANCREAS
LIVER
REPRODUCTIVE DUCT
AIRWAYS
11. The defect is in the gene coding for which chloride ion channel, which is expressed in all epithelial cells?
the cystic fibrosis transmembrane conductance regulator (CFTR),
the cystic fibrosis transmembrane conductance regulator (CFTCR),
12. CFTR and B2 receptors are linked together by EBP50, what cytoskeleton protein is EBP50 derived from?
