clinically important proteins

?

1. what is not a symptom of cushing's syndrome (excess cortisol)?

  • muscle weakness
  • truncal obesity
  • hypotension
  • androgen excess leading to hirsuitism (hair growth in women)
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Other questions in this quiz

2. what is not a symptom of hypothyroidism?

  • slow heart rate
  • weight gain and fatigue
  • high T4 and T3
  • increased TSH

3. what is not a feature of energy deprivation?

  • long symptom-free interval - can occur in older children after periods of prolonged fasting
  • symptoms are due to deficiency in ATP production or utilization
  • MCAD tests= low glucose, metabolic acidosis in blood gases, low plasma and urine ketone bodies, increases medium-chain fatty acids, plasma acylcarnitines show increased medium chain, fatty acids
  • hypoglycaemia and sudden death
  • MCAD (medium-chain acyl CoA dehydrogenase deficiency) = floppiness, heart failure, cardiomyopathy, circulatory collapse, raised lactic acid, malformations = improvement after glucose infusion

4. what is not a function of PO4?

  • low energy phosphates (ATP, GTP)
  • substrate for mineralisation (production of hydroxyapatite)

5. what is false about the parathyroid hormone receptor (PTHr)

  • primary stimulates ammonia secretion
  • PTH-NH2 terminal binds to extracellular receptor site (trans-membrane adenyl cyclase)
  • stimulates renal tubular calcium reabsorbtion and phosphate excretion
  • secondary stimulates hydroxylation of Vitamine D

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