Topic 2; Cell Membrane

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Describe the structure of a phospholipid (3 points)
Phosphate head attached to a glycerol molecule. 2 fatty acid tails attached to the oxygen molecules of the glycerol.
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Explain why phospholipids are amphipathic.
One end will mix with water while the other end won't; one end is hydrophilic and the other hydrophobic.
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Give the difference between glycolipids and glycoproteins
Glycolipids are lipids with a carbohydrate molecule attached while glycoproteins are proteins with carbohydrate molecules attached.
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Why is a the phosphate head of a phospholipid polar?
Because the molecule has an uneven distribution of electrons, causing it to have a slight charge.
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What does the 'fluid' part of 'fluid mosaic model' refer to?
Shows that some parts of the membrane can move around freely if they're not attached to other parts of the cell.
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What was the protein-lipid sandwich model and why didn't it work?
3-layered molecule based on electron micrographs showing dark outer layers (proteins) and a lighter region (lipids). Didn't factor in the behaviour of lipids due to their molecules hydrophilic and hydrophobic nature.
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How were integral proteins proven?
Membrane was frozen and then fractured along a weak point between the lipid layers. Revealed a smooth, mosaic-like structure due to dispersed integral proteins.
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Explain 2 more pieces of evidence for a phospholipid bilayer.
Fusing labeled mice and human cells saw complete intermixing of the respective cell's proteins, showing proteins could diffuse through the membrane. Latin, when labeled and mixed with membrane samples, only bound with the outer surface membrane.
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How do lipids with unsaturated fats affect the membrane?
The 'kink' in the hydrocarbon tail of the unsaturated fact affects how closely the phospholipids can fit together so more movement is possible.
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What is the role of cholesterol in the cell membrane?
Cholesterol sits between the phospholipids and maintains the fluidity of the membrane by affecting the movement of the phospholipids (ie. less cholesterol = freezer movement of the phospholipids)
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Other cards in this set

Card 2

Front

Explain why phospholipids are amphipathic.

Back

One end will mix with water while the other end won't; one end is hydrophilic and the other hydrophobic.

Card 3

Front

Give the difference between glycolipids and glycoproteins

Back

Preview of the front of card 3

Card 4

Front

Why is a the phosphate head of a phospholipid polar?

Back

Preview of the front of card 4

Card 5

Front

What does the 'fluid' part of 'fluid mosaic model' refer to?

Back

Preview of the front of card 5
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