Back to quiz

6. what is false about AML blood tests?

  • WBCs are myeloperoxidase positive
  • chemotherapy leads to complete remission in 80-90% of young patients and cure in 45%
  • normocytic, hyperchromic aneamia
  • >20% WBCs are blast cells in blood film

7. what is not an outcome of multiple myeloma

  • paraprotein in serum and/or urine
  • palliative care is cruicial as it is very painful
  • 60% 10yr survival rate
  • pancytopenia
  • >20% of plasma cells in bone marrow

8. what is false about acute myloid leukaemia?

  • malaise, fever and sweats due to metabolism to make cells
  • increase in B and T cells
  • causes pancytopenia
  • uncontrolled proliferation of myeloid stem cells resulting in large numbers of immature stem cells

9. what is CA 15-3 antigen a marker for?

  • advanced adenocarcinoma
  • pancriatic, gastric, colorectal carcinoma
  • breast cancer
  • epithelial ovarian cancer/ intra-abdominal cancers

10. what is not a cause of blood cancer?

  • myelodysplasia (pre-cancer)
  • genetic predispositions
  • radiation exposure
  • previous chemotherapy with alkylating agents

11. what is not a type of blood cancer?

  • chronic lymphoid leukeumia
  • myeloma
  • chronic myeloid leukeumia
  • lymphoma
  • acute myeloid leukeumia
  • acute lymphoid leukeumia

12. what is false about outcomes of hodgkin lymphoma blood tests?

  • lymphopenia and thrombocytopenia in early stage
  • lymph node biopsy needed
  • 80% 10yr survival rate with high cure rates
  • normocytic, normochromic anaemia
  • high eosinophil and neutrophil count

13. what is false about outcomes of non-hodgkins lymphoma blood tests?

  • 63% 10yr survival rate, responds well to chemo but no cure
  • microcytic, normochromic anaemia
  • may be due to autoimmune haemolytic anaemia

14. what is hodgekins lymphoma?

  • cancer of the clonal plasma cells in the bone marrow (B cells) which secrete Ig paraprotein
  • malignant B cells accumulate in lymph nodes, however tumour is predominately inflammatory cells
  • large group of lymphoid tumours (B-cells) with more variable presentation

15. what is not a sign or symptom of multiple myeloma?

  • renal failure and hypercalcaemia
  • amyloidosis (abnormally folded proteins)
  • leukocytosis
  • bone pain and fractures

16. what is CA 125 antigen a marker for (raised in 50% of all cases)?

  • breast cancer
  • epithelial ovarian cancer/ intra-abdominal cancers
  • pancriatic, gastric, colorectal carcinoma
  • advanced adenocarcinoma

17. what is false about chronic myeloid leukaemia?

  • leukostatis = leukocyte clumping, hepatomegaly, splenomegaly
  • 50% 5 yr survival
  • large numbers of circulating myloblasts
  • associated with presence of philadelphia chromosome (oncogene)
  • increases LDH and urate
  • may cause gout due to rapid cell turnover causing purine release leading to uric acid

18. what are the signs/symptoms are not characteristic of lymphoma?

  • disease spreads via lymphatic chain
  • assymmetrical and painless lymphadenopathy
  • fractures
  • splenomegaly