How does glutamate activation of its receptor resulting in an EPSP which makes it easier to fire an action potential?
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Card 7
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Why does the activation of glycine receptors result in an Inhibitory Postsynaptic Synapse Currents?
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Card 8
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What is the proper name for startle syndrome?
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Card 9
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Hyperekplexia (GlyR mutations) in infants is characterised by; hypertonia (increases the risk of SIDS), enhanced startle reflex, apnea. The symptoms are life threatening and induced by auditory and tactile stimuli. What is different in adults?
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Card 10
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Clonazepam which is a benzodiazepine that activates GABAr Receptors, why is this an effective treatment for Hyperekplexia?
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Card 11
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When over expressing GlyR alpha subunit mutant in xenopus oocytes and comparing the currents produced at different concs of Glycine what was observed?
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Card 12
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Would a normalised response curve showing the impact of mutations in GlyR's alpha subunit compared to beta find that they are equally responsible for the channel's sensitivity?
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Card 13
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In addition to giving rise to smaller currents, how else does the P250T mutation in GlyR differ from WT proteins
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Card 14
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How are recessive heterozygous GlyR mutations characterized in their expression of GlyR receptors.
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Card 15
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What were the two main observations from GlyR 271Q transgenic mice?
