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6. what is not indicative of homogenous patterns in anti-DNA testing?
- in metaphase there is smooth staining of the chromosomal region
- in metaphase there is complete staining of the chromosomal area
- in interphase, there is smooth staining of the entire nucleus, the nucleoli may not stain
7. what is not indicative of speckled patterns in anti-DNA testing?
- in metaphase, mitotic cells show no staining in the chromosome area but the region outside the chromosome will stain with variable intensity
- nucleoli stain completely
- interphase cells show speckled staining in the nucleus
8. what is not an organ specific form of autoimmunity?
- systemic rheumatic diseases (systemic lupus erythematosus)
- myaesthenia gravis (Ab to AChR)
- Autoimmune haemolytic anaemia (Ab to RBC Ag initiate haemolysis)
9. what is not a test for Systemic Lupus Erythematosus?
10. What is not a test for Sjogren's?
11. what is not indicative of nucleolar patterns in anti-DNA testing?
- interphase cells have staining in nucleoli and mitochondria
- in metaphase, mitotic cells show variable staining depending on the antigen involved
12. what is not a test for Systemic sclerosis?
13. what is false about anti-ENA tests to confirm nucleolar pattern?
- Anti-RO-52 = dermomyositis
- Anti-SRP = polymyositis
- Anti-JO-1 = dermomyositis
- Anti-RNP = systemic sclerosis
- Anti-SC1 70 = systemic sclerosis