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6. what is not indicative of homogenous patterns in anti-DNA testing?

  • in metaphase there is smooth staining of the chromosomal region
  • in metaphase there is complete staining of the chromosomal area
  • in interphase, there is smooth staining of the entire nucleus, the nucleoli may not stain

7. what is not indicative of speckled patterns in anti-DNA testing?

  • in metaphase, mitotic cells show no staining in the chromosome area but the region outside the chromosome will stain with variable intensity
  • nucleoli stain completely
  • interphase cells show speckled staining in the nucleus

8. what is not an organ specific form of autoimmunity?

  • systemic rheumatic diseases (systemic lupus erythematosus)
  • myaesthenia gravis (Ab to AChR)
  • Autoimmune haemolytic anaemia (Ab to RBC Ag initiate haemolysis)

9. what is not a test for Systemic Lupus Erythematosus?

  • RO-52
  • ds-DNA
  • SM

10. What is not a test for Sjogren's?

  • SSB (LA)
  • SM
  • SSA (RO)

11. what is not indicative of nucleolar patterns in anti-DNA testing?

  • interphase cells have staining in nucleoli and mitochondria
  • in metaphase, mitotic cells show variable staining depending on the antigen involved

12. what is not a test for Systemic sclerosis?

  • RNP
  • JO-1
  • SRP
  • SC1-70

13. what is false about anti-ENA tests to confirm nucleolar pattern?

  • Anti-RO-52 = dermomyositis
  • Anti-SRP = polymyositis
  • Anti-JO-1 = dermomyositis
  • Anti-RNP = systemic sclerosis
  • Anti-SC1 70 = systemic sclerosis